<p><em>Abies pindrow</em> is widely used in traditional practice for the treatment of diarrhea and bronchitis and the present study was designed to validate its folkloric uses. The crude extract of <em>A. pindrow</em> inhibit spontaneously contracting (1-10 mg/mL) and high K<sup>+</sup> (80 mM)-induced pre-contracted rabbit jejun-um (3 mg/mL) in concentration dependent manner. A rightward shift in Ca<sup>+2</sup> concentration response curves was seen in the presence of crude extract (0.1-0.3), similar to verapamil. In isolated tracheal tissue, <em>A. pindrow</em> inhibited, high K<sup>+</sup> and carbachol (1 µM)-induced contractions, at 3 mg/mL and 10 mg/mL respectively, similar to that caused by verapamil. These results indicate the presence of calcium channels blocked activity in crude extract of <em>A. pindrow</em>, which provide sound basis for medicinal uses of<em> A. pindrow</em> in diarrhea and bronchitis. </p><p> </p>
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