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Chronic disease like kidney failure, heart disease, cancer etc. is the major cause of deaths now days worldwide. Especially for the females the most dangerous type of disease from which the women of every age group are suffering especially the middle age group women’s is the breast cancer. To detect this type of disease at an early stage is a challenging task. In order to predict the breast cancer at an early stage classification algorithm of high accuracy and less error rate are desirable. In this research work we have used 4 classification algorithms K-NN, J48, Logistic regression and Bayes Net for building the predictive model, also the wrapper method of feature selection is used to enhance the accuracy rate and reduce the error rate of the used classifiers. To carry out this research we have used Wisconsin Diagnostic Breast Cancer dataset which contains 569 instances along with 32 attributes and a class attribute which will predict the type of cancer i.e. Benign or Malignant.

Background:: Breast cancer is one of the diseases which cause number of deaths ever year across the globe, early detection and diagnosis of such type of disease is a challenging task in order to reduce the number of deaths. Now a days various techniques of machine learning and data mining are used for medical diagnosis which has proven there metal by which prediction can be done for the chronic diseases like cancer which can save the life’s of the patients suffering from such type of disease. The major concern of this study is to find the prediction accuracy of the classification algorithms like Support Vector Machine, J48, Naïve Bayes and Random Forest and to suggest the best algorithm. Objective:: The objective of this study is to assess the prediction accuracy of the classification algorithms in terms of efficiency and effectiveness. Method:: This paper provides a detailed analysis of the classification algorithms like Support Vector Machine, J48, Naïve Bayes and Random Forest in terms of their prediction accuracy by applying 10 fold cross validation technique on the Wisconsin Diagnostic Breast Cancer dataset using WEKA open source tool. Results:: The result of this study states that Support Vector Machine has achieved the highest prediction accuracy of 97.89 % with low error rate of 0.14%. Conclusion:: This paper provides a clear view over the performance of the classification algorithms in terms of their predicting ability which provides a helping hand to the medical practitioners to diagnose the chronic disease like breast cancer effectively.

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