Background: Schistosomiasis is a major cause of morbidity in sub-Saharan Africa where almost 90% of cases are found. In the last decade, prevention and control activities have scaled up, with a focus on interventions delivered in community settings. The aim of this review is to assess the impact of community-based interventions (CBIs) on the prevalence and infection intensity of schistosomiasis in sub-Saharan Africa. A systematic review was published on this topic in 2014, but there have subsequently been several new studies published which are included in this updated review. Method: Five electronic databases were searched for studies relating to schistosomiasis and CBIs published since 2013 to update the previous review published in 2014. Titles, abstracts, and full texts were screened according to predefined eligibility criteria by two independent reviewers. Data were extracted in duplicate and a meta-analysis of included studies was conducted.Results: A total of 2329 de-duplicated titles were screened by two independent reviewers, and 17 studies were included in the review, 14 of which are included in the meta-analysis. Findings from the meta-analysis suggest that CBIs reduce the prevalence of Schistosoma mansoni by 46% (RR: 0.54, 95% CI [0.44, 0.67]) and S. haematobium by 56% (RR: 0.44, 95% CI [0.25, 0.77]). Both school-based and community-wide treatment are effective platforms for achieving reductions in prevalence. Only three studies reported growth outcomes or anaemia and found mixed effects.Conclusions: Most interventions included in this review delivered drug treatment, and results suggest that these are effective in reducing prevalence. While drug treatment can have immediate beneficial health effects, reinfection is likely to continue if unsafe water contact continues. Therefore, interventions that both prevent infection and reduce prevalence and intensity of infection are required.
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