Vaccination is one of the several known triggers of Parsonage-Turner syndrome
(PTS). This report describes 2 individuals with clinical presentations of
PTS whose symptoms began 13 hours and 18 days following receipt of the
Pfizer-BioNTech BNT162b2 and Moderna mRNA-1273 COVID-19 vaccine,
respectively. The diagnosis of PTS was confirmed using both
electrodiagnostic testing and 3 Tesla magnetic resonance (MR) neurography.
While research is needed to understand the association between PTS and
COVID-19 vaccination, MR neurography may be used to confirm suspected cases
of PTS as COVID-19 vaccines continue to be distributed worldwide.
Introduction
In this study we tested the hypothesis that fascicular constrictions (FCs) of the median nerve proximal to the elbow joint characterize anterior interosseous nerve syndrome (AINS).
Methods
Magnetic resonance neurography (MRN) and ultrasound (US) examinations were evaluated in 45 patients with clinically suspected AINS. All 22 patients at site 1 underwent MRN and 8 underwent US; all 23 patients at site 2 underwent US.
Results
Median nerve FCs were identified in all MRN cases; FCs and/or fascicular enlargements were identified in 88% of US cases. Most FCs were in the mediannerve posterior/posteromedial region and were proximal to the elbow joint line (mean distance: MRN, 5.4 cm; US, 7.5 cm), with the exception of a single FC (located 1 cm distal). No extrinsic compression of median or anterior interosseous nerves was identified in the arm or forearm.
Discussion
AINS is a noncompressive neuropathy characterized by median nerve FCs in the arm.
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