Preventing malaria in children is often neglected. Prevention is very important, as malaria is still a significant cause of childhood mortality. Parents must be aware that the same measures must be taken by children to avoid being bitten by mosquitoes. Chemoprophylaxis with mefloquine, atovaquone-proguanil, doxycycline, or chloroquine is advised. The correct dose must be given, at the correct dosing interval. The choice of drug depends on several factors, such as cost, side-effects, and other drug intake. Parents must be educated on the symptoms of malaria, as making a prompt diagnosis can reduce the incidence of further complications.Peer reviewed.