To compare the set-up uncertainties in breast radiation therapy using two different immobilization methods: vacuum cushion (VC) and standard breast board (BB). The data set comprises of 26 breast cases were divided into two groups based on the type of immobilization used for their radiotherapy treatment, either intensity-modulated radiotherapy (IMRT) or volumetric arc modulated radiotherapy (VMAT). The vacuum cushion group consisted of 14 patients with 143 exposures and the breast board group consisted of 12 patients with 120 exposures. Set-up

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