Background: Trauma-induced ulcers constitute one of the painful abnormalities affecting the oral cavity about which numerous individuals complain. The prevalence of traumatic ulcers (15-30% of cases) is relatively high compared to other oral lesions. Unfortunately, the use of anti-inflammatory drugs classified as steroids can lead to contraindications and serious side effects. Hence, the use of natural ingredients represents an alternative treatment. One such ingredient is red pomegranate containing bioactive elements acting as anti-inflammatory, antibacterial, antimicrobial, and antioxidant agents which accelerate the healing process in traumatic ulcers. Purpose: The aim of this study was to determine the effects of the topical application of red pomegranate (Punica granatum Linn) extract on the healing process in traumatic ulcers in Wistar rats. Methods: 24 male rats, aged 2-3 months, were divided into six groups, namely; two control groups (PC: triamcinolone acetonide and NC: sterile aquades) and four treatment groups (red pomegranate extract gel at respective concentrations of 12.5%, 25%, 50% and 75%). A traumatic ulcer was subsequently created using a flame-shaped burnisher tip 2mm in diameter and heated for ±15 seconds. The diameter traumatic ulcer of each research subject was measured and observed until it healed within the remedial parameters determined by means of a UNC-15 periodontal probe which had been placed on it. The data obtained was analyzed using Kruskal-Wallis and Mann-Whitney tests. Results: Topically applied red pomegranate extract gel can reduce the width of the ulcerated area, while also accelerating traumatic ulcer healing. There was a significant difference in the healing time between the group using red pomegranate extract gel at a concentration of 75% and the positive control group using 0.1% triamcinolone acetonide with p=0. 44 (p<0.05). Conclusion: Red pomegranate extract gel possesses the ability to accelerate the healing process in traumatic ulcers. The most effective concentration of red pomegranate extract gel at accelerating the healing process in traumatic ulcers is 75%.
Hospital Information Management System (HIMS) was part of a health information system that provided relevant information resources throughout the organization to supported effective decision made and hospital administration. This studied aims to analyzed the impact of system quality, system users, and organizations in the utilization of HIMS performanced. The type of researched used was the type of explanatory researched. The population in this studied amounted to 258 and 158 samples. Based on the tested results there was the influenced of system quality on system users with t statistics 3,219 (t statistics> t table 1.96). In addition there was no effected of system quality on the organization with t statistics 0.483 and there was no organizational influenced on the user system with t statistics 1.489. Furthermore there was the effected of system users on the utilization of SIMRS performanced with t statistics of 5.838 and there was an organizational influenced on the utilization of HIMS performanced with t statistics 3.589. The results were interrelated between variables so that to realized the utilization of HIMS performanced. <br/>Keywords: System quality, System Users, Organization, Utilization of Abstrak
Abstrake-Jurnal Pustaka Kesehatan, vol. 6 (no. 1), Januari, 2018 192 Latar Belakang: Staphylococcus aureus merupakan mikroorganisme yang paling banyak dijumpai pada angular cheilitis. Angular cheilitis adalah keradangan pada salah satu sudut mulut atau kedua sudut mulut dapat meluas melibatkan komisura bibir dan kulit sekitarnya. Prevalensi terjadinya angular cheilitis yaitu 0,2-15,1% pada anak-anak dan 0,7-3,8% pada orang dewasa. Salah satu alternatif pengobatan dengan menggunakan tanaman herbal, yaitu buah delima merah. Buah delima merah mengandung flavanoid, tannin, dan alkaloid yang diduga sebagai antibakteri. Tujuan: untuk mengetahui daya hambat ekstrak buah delima merah terhadap pertumbuhan Staphylococcus aureus.Metode Penelitian: metode disk difusi dengan menggunakan 6 sampel pada setiap kelompok penelitian. Kelompok penelitian terdiri dari 4 kelompok perlakuan (ekstrak buah delima merah konsentrasi 25%, 50%, 75% dan 100%), kelompok kontrol positif (asam fusidat), dan kelompok kontrol negatif (aquades steril). Analisis data menggunakan uji One Way Anova dan uji LSD (Least Significant Difference). Hasil dan simpulan: ekstrak buah delima merah memiliki kemampuan menghambat pertumbuhan Staphylococcus aureus. Konsentrasi ekstrak buah delima merah yang memiliki daya hambat terbesar terhadap pertumbuhan S. aureus, yaitu konsentrasi 75% dan 100%.
Background: A geographic tongue is an inflammatory lesion of the tongue accompanied with atrophy formation of papilla or depapilation of the filiform papillae. The geographic tongue usually appears together with the appearance of the fissure tongue, a midline, multiple, fissure on the surface of the tongue that expands from front to back and has various patterns. Predisposing factors of geographic tongue and fissure tongue are nutritional deficiencies and stress. Oral candidiasis is one of the fungal infections that affect the oral mucosa caused by the fungus Candida albicans. Predisposing factors of oral candidiasis e.g. stress, and smoking habits. Case: 64-year-old male patient with a clinical appearance on the dorsum of the tongue in a bracelet-like form with depapilation, vertical fissure 3 mm deep and thick white plaque which could be scraped and felt painful. Diagnosis: geographic tongue, fissure tongue and oral candidiasis. Therapy: aloe vera in oral solution as antiinflammatory and analgesic, Nystatin oral suspension functions as a topical antifungal medicine, multivitamin Becomzet (Vitamin B complex, A, C, E, and Zinc) as a multivitamin. Conclusion: after therapy using aloe vera solution, nystantin becomzet controls both patients had undergone a healing process in both the case of geographic tongue, fissure tongue and oral candidiasis. Keywords: Geographic tongue, Candidasis
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