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It was a quasi-experimental research with pretest and posttest design.  It was instigated by the low of student learning achievement on Thermochemistry lesson.  This research aimed at knowing the effect of implementing Teams Games Tournament (TGT) learning model with Kokami media toward student learning achievement on Thermochemistry lesson.  The subjects of this research were the eleventh-grade students of Natural Science of State Senior High School 1 Tambusai Utara.  Simple random sampling technique was used in this research, and it was obtained two classes—the eleventh-grade students of Natural Science 2 as the experimental group and the students of Natural Science 1 as the control group.  The data were collected by using observation, preliminary data test that was homogeneity, final data tests that were pretest and posttest, and documentation.  Kp formula was used to know the effect of implementing TGT learning model with Kokami media toward student learning achievement.  The effect difference was analyzed by using independent sample t-test.  The analysis results of preliminary and final data showed that tobserved was 3.184 and ttable was 1.995 at 0.05 significant level.  The score of tobserved was higher than ttable, so H0 was rejected and Ha was accepted.  It meant that there was an effect of implementing TGT learning model with Kokami media toward student learning achievement on Thermochemistry lesson at the eleventh grade of Natural Science of State Senior High School 1 Tambusai Utara, and the effect was 16.3%.Keywords: Learning Achievement, Teams Games Tournament (TGT), Kokami Media, Thermochemistry

Background: Ficus deltoidea is a medicinal plant known for treatment by ethnic Dayaks, Kalimantan and called Tabat Barito. Empirically, the majority of Tabat Barito leaves are used to treat candidiasis. Scientific data on F. deltoidea activity in its activity against candidiasis or candida are still minimal. Metabolite profiling from the most active fraction of F. deltoidea against Candida has not been reported. Objectives: This study aimed to explore the most active part of F. deltoidea leaves against C. albicans by obtaining the most active fraction and identification of compounds in the most active fraction through metabolite profiling using UPLC-QToF-MS/ MS. Methods: The leaves were macerated using solvents with an increase in polarity, fractionation was done by column chromatography, while antifungal activity assay was carried out by diffusion method. Metabolite profiling was done using LC-MS/MS. Results: Assay results of extracts from F. deltoidea leaves against C. albicans showed that the best activity was owned by ethyl acetate extracts, with an inhibition zone of more than 10 mm. The strongest activity against C. albicans was shown by FrEA5 with an inhibition zone of 30.67 ± 1.155 mm, stronger than Voriconazole as a positive control with inhibition zone: 19.75 ± 0.5 mm. The metabolites that can be identified in FrEA5 were Nigeglanine; 1,1,2,3,3-Pentamethylindane; and 1,1'-(1,1-Ethenediyl)bis(3-methylpiperazine). Conclusion:This research shows that FrEA5 is the most active fraction of F. deltoidea leaves against C. albicans and the compounds contained in FrEA5 include Nigeglanine; 1,1,2,3,3-Pentamethylindane; and 1,1'-(1,1-Ethenedyl)bis(3methylpiperazine).

Bitter melon (Momordica charantia L.) is a type of medicinal plant that is widely used by the public. Charantin is one of the nutritious compounds contained in bitter melon. Charantin compounds can be used to reduce glucose levels in the blood so that it is widely used as a diabetes medicine. The research aims to determine the effect of variations in the concentration of amprotab as a desintegrant on the physical properties of Pare (Momordica charantia L.) extract tablets has been conducted. Viscous extract was made by maceration method by using ethanol 96%. Tablets made by wet granulation method in two different desintegrant concentration of 9,6% and 18%. Dried granule tested with flowability, angle of repose and indeks of compressibility. Tablet evaluation includes uniformity of weight test, friability test, hardness test and disintegration test. The results showed that formula with amprotab as desintegration at 9,6 % concentration was able to produce tablets that met the requirements. Variation in concentration of desintegrant material take effect on the uniformity of weight, hardness friability and disintegration time.