The efficacy of triclabendazole (TCBZ) against natural infections with Fasciola gigantica was evaluated in a field study using 102 Indonesian cattle. The animals were divided into two groups; one received TCBZ at 12 mg/kg orally every eight weeks for one year while the other remained untreated. Relative to controls the Fasciola faecal egg count in treated animals was significantly reduced (P less than 0.01) to almost zero at all observations. There were no differences between the groups in blood values and body mass gain. Plasma glutamate dehydrogenase (GLDH) levels in treated animals were reduced to within normal values, whereas those in controls remained above normal throughout. Although plasma gamma glutamyl transferase (GGT) levels remained within the normal range in both groups they were consistently higher in control than in treated animals. However, both GLDH and GGT levels in control animals were considerably lower than those reported by others in experimental low-level chronic fasciolosis, which suggests that only mild liver damage was caused by small numbers of F. gigantica in these animals. In addition to considerations of disease prevalence and economic data from abattoirs, control strategies for fasciolosis in Indonesian cattle require an evaluation of losses due to subclinical disease.
Alternatif untuk mengendalikan dan menanggulangi mewabahnya Coronavirus Disease (Covid19) yaitu melakukan sosialisasi dan peyuluhan sesuai protokoler kesehatan. Dukungan serta partisipasi masyarakat menjadi perihal penting dalam memutus mata rantai penyebarannya dengan mematuhi protokoler kesehatan yang telah ditetapkan oleh pemerintah. Kecenderungan masyarakat Indonesia yang heterogen, khusunya masyarakat kabupaten pamekasan yang terbiasa hidup berdampingan dan terkesan apatis terhadap kondisi yang berkembang saat ini. Permasalahan di kabupaten pamekasan melalui Data yang dirilis pemerintah dengan klasifikasi terpapar virus ialah ODP 582, PDP 104, Positif Covid 109 Kecamatan. Solusi permasalahan adalah memberikan sosialisasi serta penyuluhan. Tujuan kegiatan pengabdian pada masyarakat (PPM) yaitu memberikan pemahaman serta edukasi terhadap masyarakat. Kegiatan PPM dilaksanakan di Desa Panglegur Kecamatan Tlanakan pada bulan Juni –Juli 2020. Kelompok sasaran PPM adalah masyarakat desa panglegur. Hasil kegiatan sosialisasi serta penyuluhan pada masyarakat ialah masyarakat mulai memahami bahaya dan pencegahan serta penularan covid19. Untuk mengantisipasi penyebaran dan penularannya di butuhkan strategi yang kuat dengan bergotong royong antara pemerintah, stakeholder serta masyarakat dalam meminimalisir bertambahnya cluster baru positif Covid 19 di kabupaten pamekasan.
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