Background: Swine influenza is an infection caused by any one of several types of swine influenza viruses. Swine influenza virus (SIV) or swine-origin influenza virus (S-OIV) is any strain of the influenza family of viruses that is endemic in pigs. As of 2009, the known SIV strains include influenza C and the subtypes of influenza A known as H1N1, H1N2, H2N1, H3N1, H3N2, and H2N3. Subjects and Methods: The patients with clinical features of Influenza like illness were enrolled. A complete clinical examination was carried out and relevant investigations done and documented in the proforma. Results: Most common symptoms at presentation were cough (93%), fever (92%) followed by sore throat (76%). Breathlessness was found in 28.76% of patients at presentation of which nearly 3/4th died. 72% patient died of ARDS and out of which 79% were female. Conclusion: Most common cause of death was acute respiratory distress syndrome (72%) followed by secondary infection with septicemia.