Punica granatum Linn. is also known as Pomegranate is a fruit-bearing deciduous shrub, having potential anthelmintic activity as, In-vitro anthelmintic activity of fruit ethanolic extract of Punica granatum linn. was evaluated using Paramphistomum cervi, Moniezia expansa, Avitellina Centripunctata and Trichuris ovis, sustained on time and concentration of extract, standard anthelmintic used was fenbendazole. Complete cessation of motility and mortality were recorded contemplating parasitic activity. Study records complete cessation of motility of worms after increase in concentration of the Punica granatum linn. fruit extract. After 15, 14 & 13 hours of exposure in concentrations of 25, 50 & 75 mg/ml respectively, there was complete mortality of study group of parasites. Before which, complete cessation of motility of worms after 9.5, 8.5 & 7.5 hours of exposure detected.