Background: This study was conducted to evaluate the clinical, pathological and radiological profile of suspected lung malignancy and its correlation with bronchoscopic findings.Methods: A hospital based prospective study was conducted in the department of pulmonary medicine on 74 patients who were suspected with lung malignancy, clinically or radiologically. Following a detailed clinical examination, chest x-ray and CECT thorax, patients were included in the study and were subjected to bronchoscopy. Based on the bronchoscopic findings BAL, TBNA, forceps biopsy and TBLB were performed.Results: Out of 74 patients, most of them belonged to the age group of 51-65 years. Majority were males. Cough was the most common symptom. 51 patients had weight loss and 48 had associated reduced appetite. 50 (67.6%) were smokers. Out of them 43 (86%) were beedi smokers. In CT thorax, most common presentation was mass lesion followed by consolidation, nodules and interstial thickening. Right side was the most common side involved. Bronchoscopy revealed intraluminal growth as the most common finding and the most common pattern noted was fungating growth. Squamous cell carcinoma was the most common cell type noted in 9 (27.03%) followed by adenocarcinoma and small cell carcinoma. Squamous cell carcinoma presented more commonly as central mass with intraluminal growth and adenocarcinoma presented more commonly as peripheral lesions with extraluminal compression in bronchoscopy.Conclusions: Elderly smokers with cough and loss of appetite with weight loss can be suspicious of lung malignancy. CT and bronchoscopy are essential for the diagnosis of lung malignancy.
Tuberculosis has been one of the major public health concerns since many years now. Around 15-20% of TB cases are found to be extrapulmonary1. Diagnosis is challenging due to its pauci bacillary nature2. The objective of this study is to determine the pattern and sites of extra pulmonary tuberculosis in patients presenting to our tertiary hospital. Materials and Methods- This is a hospital based retrospective observational study. A total of 73 patients were included in the study. Study period was 1 year (Jan 2019 – Jan 2020). Data regarding the various samples, sites and various tests done – AFB, CBNAAT were collected. Both microbiologically or clinically diagnosed extrapulmonary tuberculosis were included. Records were obtained from the medical records maintained in the DOTS centre of our hospital. Results-Majority of the patients belonged to the age group of 21-40 years (42.5%) with male (61.6%) predominance. Most common extrapulmonary site was pleura (27.8%) and least common was endometrium (1.4%). 71.2% of the cases were clinically diagnosed and 28.8% were microbiologically conrmed. CBNAAT detected TB bacilli in 23.3% of the cases. Conclusion- In our study the most common site of extrapulmonary tuberculosis was pleura presenting as pleural effusion and in majority of them TB bacilli could not be detected.
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