Herein, two techniques to optimize the production process of large‐format lithium‐ion cells for plug‐in hybrid electric vehicles using data‐driven methods are introduced and demonstrated. The first approach uses standard settings of the quality influencing factors to maximize the number of produced electrode sheets that meet predefined quality specifications. The second approach uses statistical methods to determine the levels of the quality influencing factors of a certain process that optimizes all quality parameters of the corresponding product jointly.

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