Abstract-Networks-on-Chip are seen as promising interconnect solutions, offering the advantages of scalability and high frequency operation which the traditional bus interconnects lack. Several NoC implementations have been presented in the literature, some of them having mature tool-flows and ecosystems. The main differentiating factor between the various implementations are the services and communication patters they offer to the enduser. In this paper we present dAElite, a TDM Network-on-Chip that offers a unique combinations of features, namely guaranteed bandwidth and latency per connection, built-in support for multicast, and a short connection set-up time. While our NoC was designed from the ground up, we leverage on existing tools for network dimensioning, analysis and instantiation. We have implemented and tested our proposal in hardware and we found it to compare favorably to the other NoCs in terms of hardware area. Compared with aelite, which is closest in terms of offered services our network offers connection set-up times faster by a factor of 10 network, traversal latencies decreased by 33%, and improved bandwidth.
Schizophrenia is the most severe of the mental illnesses and affects approximately 0.8% of the population in Western societies. Postmortem and neuroimaging studies show that patients with schizophrenia have slightly larger cerebral ventricles than normal and a decrease in cortical volume, most markedly in the left temporal lobe. These changes are present at diagnosis and appear to show little change over extended periods of follow‐up. Associated findings such as lack of normal cerebral asymmetry and cytoarchitectonic changes suggestive of impaired migration of cortical neurons implicate aberrant neurodevelopment. Schizophrenics also show an excess of pregnancy and birth complications, and an association with prenatal exposure to maternal influenza. These and reports of abnormal psychological development in pre‐schizophrenic children add further support to the theory that the disorder has neurodevelopmental origins.
We aimed to provide in vitro data on the neutralization capacity of different monoclonal antibody (mAb) preparations against the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) delta and omicron variant, respectively, and describe the in vivo RNA kinetics of coronavirus disease 2019 (COVID‐19) patients treated with the respective mAbs. Virus neutralization assays were performed to assess the neutralizing effect of the mAb formulations casirivimab/imdevimab and sotrovimab on the SARS‐CoV‐2 delta and omicron variant. Additionally, respiratory tract SARS‐CoV‐2 RNA kinetics are provided for 25 COVID‐19 patients infected with either delta variant (n = 18) or omicron variant (n = 7) treated with the respective mAb formulations during their hospital stay. In the virus neutralization assay, sotrovimab exhibits neutralizing capacity at therapeutically achievable concentrations against the SARS‐CoV‐2 delta and omicron variant. In contrast, casivirimab/imdevimab had neutralizing capacity against the delta variant but failed neutralization against the omicron variant except for a very high concentration above the currently recommended therapeutic dosage. In patients with delta variant infections treated with casivirimab/imdevimab, we observed a rapid decrease of respiratory viral RNA at day 3 after mAb therapy. In contrast, no such prompt decline was observed in patients with delta variant or omicron variant infections receiving sotrovimab.
The following article analysis the influence of the money supply and interest rate over inflation. In order to prove our assumptions we have followed the date available in the United States and China over a period of 24 years . These two countries are so different and yet similar in many ways. Although China does not support USA and tries to outweigh USA as the most important economy in the world, it is an important pioneer of promoting the US dollar, by keeping its exchange rate pegged to the USD. This research will prove that these economies depend on each other. The article presents a different statistical approach in analyzing the effects of money supply and interest on inflation but not the other way around. Different monetary policies embraced by China and USA can be the starting point in estimating inflation by using past data and analyzing monetary policies adopted along the years. The model created will present different applicability on China and USA. This is because of the influence of the political sector over the Chinese economy and the unhealthy growth of the money supply. By using monthly data for several years in Mathlab, an approximate equation with low level of error it is desired. As long as the data are accurate, this research could create a clear and healthy image of the monetary system of an economy. The main question after this research was the high error of the equation resulted in China, although using the same statistical database. Are the data published for monetary indicators in China are accurate?
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