An instructional research-like multiweek laboratory project for a second-semester introductory general chemistry laboratory course has been developed. The ultrasonic-assisted synthesis method using low cost commercial ultrasonic cleaners has the convenience of running multiple students’ reactions simultaneously. Taking advantage of short reaction time, the green metal–organic framework project has been developed to facilitate experimental synthesis, characterization, and application of a porous material and debriefing of results during a normal laboratory period (about 3 h/class). This project provides the opportunity for instructors to introduce students to the Twelve Principles of Green Chemistry, the environmental impact of chemistry, modern solid-state analytical techniques, and a research-like experience of materials science.