Participation of female athletes in sports at all levels continues to grow exponentially, as well as the injuries they experience during play. A literature review does outline return to sport guidelines, yet few studies address the potential need for differences between male and female athletes. This commentary is a review of the literature that outlines various sports that involve both male and female overhead athletes and potential differences in upper-extremity injuries and strengths and weaknesses between sexes. This information proposes the potential need to customize returnto-sport guidelines and screens that include recommendations for overhead female athletes within their specific sport, following both injury as well as surgical intervention. Level of Evidence: V.
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