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Highlights d We define the basic transcriptome of an activated MAIT cell in mice and humans d During acute infection, the MAIT cell transcriptome is most similar to iNKT cells d After the resolution of infection, MAIT cells more closely resemble gd T cells d Both human-and murine-activated MAIT cells express a strong tissue repair signature

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The ability of fish oil to decrease TNF-alpha production is influenced by inherent TNF-alpha production and by polymorphisms in the TNF-alpha and lymphotoxin alpha genes.