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All three treatment regimens were well-tolerated. The results of this study indicate that a single dose of granisetron 10 or 40 micrograms/kg is as effective as three doses of ondansetron 0.15 mg/kg in the prevention of nausea and vomiting induced by cisplatin chemotherapy.

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A PSn2C ring containing a PC double bond is formed in the title reaction. Compound 1 is the first phosphadistannacyclobutene. The alternative formation via successive addition of two R2Sn units, formed in the equilibrium R2Sn = SnR2⇄2R2Sn, is unlikely, since an intermediate containing a PSnC ring could not be detected.