This study aims to determine the factors that influence the use of elearning.umn.ac.id on students through the framework of the Technology Acceptance Model (TAM). There are five original constructs of TAM used in this study, including perceptions of usability (PU), perceptions of ease of use (PEOU), attitudes towards use (ATU), behavioral interests (BI), and actual use (AU). There are also three external constructs used in this study, including self-efficacy (SE), system accessibility (SA), and system quality (SQ). The results obtained in this study found the level of acceptance and use of UMN e-learning for students using perceived usefulness, perceived ease of use, behavioral intention, actual use and external factors (self-efficacy, system accessibility, system quality) TAM is high. Perceived ease of use does not have any relationship to other factors, so that if the factor perceived ease of use is increased then there will not be any effect on actual use, even though it is supported by a system accessibility factor. The significant positive effect of all variable pairs has a value reduction characteristic, so if an independent factor has an increase in score of n, then the dependent factor that has a relationship with the independent variable also increases the score but decreases the value of n number with the coefficient value the total influence it has.Index Terms-e-learning, Technology Acceptance Model (TAM), self-efficacy, system accessibility, system quality.