Background and Objectives: Duodenal diverticula are a common finding in patients with biliary tract disorders. The objective of this study is to assess the diagnostic value of the magnetic resonance cholangiopancreatography (MRCP) in case of periampullary duodenal diverticula (PAD) using endoscopic cholangiopancreatography (ERCP) as a reference method.
Methods: The study population included 350 patients with known or suspected diseases of the biliary tract, liver, and pancreas. Two radiologists interpreted the image quality and the presence of PAD in agreement .
Results: In cases with a single PAD, MRCP had sensitivity 81.2%, specificity 98.6%, positive predictive value 90.9%, and negative predictive value 97%, compared to ERCP. In the case with two PAD, MRCP had sensitivity 40%, specificity 99.7%, positive predictive value 66.7% and negative predictive value 98.9%. The average volume of PAD was 3.25 cm3. In this study group patients with PAD were on average 10 years older than those without PAD (< 0.001). There was also found a significant association of PAD with choledocholithiasis (p = 0.009) and cholecystitis (p = 0.002).
Interpretation and Conclusions: In conclusion, MRCP could be used as a non-invasive diagnostic modality with acceptable sensitivity and specificity in patients with suspected PAD and biliary tract diseases.
Магнитнорезонансната холангиопанкреатография (MRCP) притежава редица предимства, включващи отсъствие на йонизираща радиация и на инвазивност, както и липса на усложнения като остър панкреатит и холангит, характерни за директните холангиографски методики. MRCP представлява метод на избор за неинвазивното изследване на вродени малформации на жлъчната и на панкреасната система. Чернодробните резекции и трансплантации заемат важно място в хирургията на жлъчното дърво и черния дроб. Ето защо доброто познаване и разбиране на анатомията, вариантите и вродените малформации е от особена важност.
The presence of a periampullary duodenal diverticulum (PDD) is often observed during upper digestive tract barium meal studies and endoscopic retrograde cholangiopancreatography (ERCP). The impact of periampullary duodenal diverticulum for the formation of gallstones in the bile duct (choledocholithiasis) is widely accepted. In this study it using logistic regression modeling the appearance of choledocholithiasis depending periampullary duodenal diverticulum, to confirm the connection between them. The resulting model allows evaluation of the estimated probability of occurrence of this complication. The model is based on the 1719 recording of endoscopic retrograde cholangiopancreatography performed in the
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.