No abstract

The patient was a 22-year-old woman, who presented with abdominal pain and palpable huge mass. The initial investigation by ultrasound examination showed a huge size heterogenous soild mass and then magnetic resonance imaging presented multilobulated, huge solid mass (16×13 cm) with heterogenous enhancement in left ovary. Serum calcium level was slightly elevated (10.6 mg/dL, normal less than 10.4 mg/dL) and cancer antigen 125 level was normal. She underwent a laparotomy and left salpingo-oophorectomy. Grossly, ovary consists of yellowish solid portion but not cystic portion and outer capsule was ruptured focally. The pathologic finding, including immunohistochemical finding, confirmed small cell carcinoma, hypercalcemic type from ovary. Now, She has been treated with adjuvant chemotherapy (cisplatin, adriamycin, etoposide, cyclophophamide). We report this case with brief review of literature.

A 21-year-old female with primary amenorrhea, sexual infantilism, and phenotypic female visited our Obstetrics and Gynecology Clinics. The patient showed elevated follicle stimulating hormone and luteinizing hormone, decreased estradiol, normal thyroidstimulating hormone and prolactin level that means hypergonadotropic hypogonadism with normal 46, XX karyotype. Under diagnostic laparoscopy, both ovaries were intact morphology, small but anatomically normal uterus and vagina. Ovarian biopsy was taken and reported abundant primodial follicles and sporadic preantral follicles. We concluded that final diagnosis is resistant ovarian syndrome.