The reaction ofp-tert-butylcalix[4larene with either tris(dimethy1amino)methylsilane or trichloromethylsilane yields 3, a novel silyl triether derivative with a pendent phenolic group, which should serve as a valuable precursor to substituted calix[4larenes. We demonstrate its utility in the high-yield synthesis of the mono-0-methylated p-tert-butylcalix[4larene 6 via 0methyl silyl compound 5.
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