Hydatid cyst may be found in almost any part of the body, but most often in the liver and the lungs. Other organs affected occasionally include the brain, muscle, kidney, heart, pancreas, adrenal, and thyroid gland. Hydatidosis located in the thyroid is an infrequent finding, even in endemic regions. This report documents a rare case with a cystic nodule in the thyroid detected by ultrasonography. The patient was a 30-year-old woman with an euthyroid multinodular goitre. Ultrasonography revealed a cystic nodule, and the ultrasonic appearance of the cyst liquid showed multiple echoes, suggesting that the nodule could be a hydatid cyst. The histopathologic examinations confirmed this to be a primary hydatid cyst of thyroid. During the differential diagnosis of the cystic thyroid lesions, hydatid disease of the thyroid gland should be considered in endemic areas. Chemotherapy is necessary to avoid recurrence. DOI: http://dx.doi.org/10.3126/ajms.v5i2.8830 Asian Journal of Medical Science, Volume-5(2) 2014: 143-145
Backgrounds: Hyperuricemia has not yet been established as cardiovascular risk factor. We aimed to study the angiographic severity in patients with coronary artery disease (CAD) and hyperuricemia.Materials and Methods: In this observational cross-sectional study we measured serum uric acid level in 82 patients of CAD who underwent coronary angiography in catheterisation laboratory of our Institution. Severity of CAD was determined on the basis of Gensini score, number of diseased vessels, critical lesions and total occlusions.Results: The prevalence of hyperuricemia in patients with CAD was 42.68% in our study. Hyperuricemia was associated with higher Gensini score (33.33±10.64 vs. 22.90±6.75, p value <0.001), number of critical lesions (1.03±0.84 vs. 0.63±0.72, p value 0.031), total occlusions (0.67±0.47 vs. 0.37±0.48, p value 0.007) and dyslipidemia (63.6% vs. 30.6%, p value 0.003) more frequently compared to normouricemic patients. And also the higher serum uric acid level was correlated with higher Gensini score (beta 0.418, t 4.430, p value <0.001, 95% CI 0.036 and 0.094) and frequent number of total occlusion (beta 0.338, t 3.589, p value 0.001, 95% CI 0.462 and 1.613).Conclusion: Hyperuricemia was associated with higher Gensini score, frequent total occlusions and critical lesions in patients with Coronary Artery Disease compared to patients with normal uric acid level and also it was significantly correlated with higher Gensini score and frequent total occlusions.Asian Journal of Medical Sciences Vol.7(2) 2015 1-4
INTRODUCTIONMajority of patients (>90%) with hypertension suffer from essential or primary hypertension, while the remaining minority have secondary hypertension. It is estimated that only one-third of patients on treatment have their blood pressures well controlled.1 A considerable percentage of poorly control falls into a category known as 'resistant hypertension' of which pathophysiology and risk factors are not fully understood. 2Resistant hypertension is defined as "Suboptimal control of blood pressure despite using three antihypertensive agents inclusive of a diuretic, and patients who need ≥4drugs to control blood pressure".2 Despite having guidelines on management of resistant hypertension, it has become a problem to control blood pressure up to recommended levels, possibly due to poor understanding of pathophysiology and risk factors. Studies have shown that older age, obesity, excessive use of alcohol, and high sodium intake are strongly correlated with poor control of hypertension.3,4 Patient factors such as compliance and knowledge, and healthcare system factors like limitation of resources and lack of reminders of appointments also plays a major role in poor blood pressure control. [5][6][7][8][9] Managing resistant hypertension is difficult and they are more likely to have target organ damage and have higher cardiovascular risks than patients with well controlled blood pressure. 10 The prevalence rate for hypertension in urban India is 29-45% in men and 25-38% in women, while data from other South Asian countries are sparse. Senior ESI PGIMSR, Maniktala, Kolkata, India,2,4,6,7 Senior Resident, Post-Graduate Trainee, Professor and HOD, Medicine, Burdwan Medical College and Hospital, Burdwan, India,3 Medical Officer, Ghatal SDH, Purba Midnapore, India,5 Post-Graduate Trainee, Medicine, Medical College, Kolkata, India A B S T R A C T Access this article online Website:http://nepjol.info/index.php/AJMS Background: To study the prevalence and associated cardiovascular risk factors in resistant hypertensive subjects among hypertensives. Methods: A descriptive cross-sectional observational study was carried out among 300 hypertensive patients attending 'Hypertension Clinic' and providing informed written consent from October 2013 to December 2013 at Burdwan Medical College and Hospital, Burdwan, West Bengal in India. A pre-tested interviewer-administered questionnaire was used for data collection. Chi-squire test and odds ratio were calculated using biomedical software. The study was approved by Ethics Review Committee of our Institution. Results: The prevalence of resistant hypertension was 23.33% among all hypertensives. The patients with Resistant hypertension were significantly associated with older age groups (>55 years) (77.1% vs. 38.3%, p value <0.001, OR 5.446, 95% CI 2.935 and 10.104), Obesity (BMI > 27.5 kg/m
Introduction: Stroke is the second leading cause of mortality worldwide. Ischemic stroke is more prevalent than hemorrhagic stroke and atherosclerosis is the major cause of ischemic stroke. The increased carotid artery intima-media thickness (CIMT) is considered to be useful indicator of early atherosclerosis. So, this study was aimed to correlate the relationship between atherosclerotic risk factors and intima-media thickness of carotid artery in patients with acute ischemic stroke. Material and Methods: In this cross-sectional study, 100 consecutive patients of acute ischemic stroke and 50 healthy relatives of patients as control were studied for presence of atherosclerotic risk factors and carotid artery intima?media thickness by B-mode Doppler ultrasonography.Results: In this age and sex matched study, higher CIMT measurement was found among patients of acute ischemic stroke than healthy controls (0.849 ± 0.196 vs 0.602 ± 0.092; p < 0.001). The CIMT was well correlated with smoking (Beta = 0.295; t = 5.728; 95% CI 0.088 to 0.181; p < 0.001); hypertension (Beta = 0.387; t = 6.518; CI 0.112 to 0.209; p < 0.001); di abetes (Beta = 0.237; t = 4.848; CI 0.074 to 0.175; p < 0.001); hypercholesterolemia (Beta = 0.292; t = 5.840; CI 0.096 to 0.195; p < 0.001), but not with age (p = 0.153). The CIMT was also found to be higher among acute ischemic stroke patients who were smoker, hypertensive, diabetic and hypercholesterolemic than non?smoker, normotensive, non-diabetic and normo-cholesterolemic respectively. Conclusion: The CIMT being indicator of atherosclerosis can be used as future predictor of ischemic stroke. DOI: http://dx.doi.org/10.3126/ajms.v6i1.10301 Asian Journal of Medical Sciences Vol.6(1) 2015 22-27
Background: Epicardial adipose tissue thickness has been considered to be a possible cardiovascular risk indicator in recent reports. Aim of this study was to evaluate the relationship of echocardiographic epicardial fat thickness (EFT) with carotid intima-media thickness (CIMT), in patients with type 2 diabetes mellitus (T2DM).Materials and Methods: In this hospital based cross sectional observational study a total of 64 patients with T2DM (mean age 54.51±6.60 years and 75.0% male) and 76 age and sex-matched non-diabetic control (mean age 54.97±6.11years and 71.1% male) were evaluated. Echocardiographic EFT and ultrasonographic CIMT were measured in all subjects.Results: Patients with T2DM had significantly increased EFT and CIMT than those of the non-diabetic controls (6.15±0.99 mm versus 4.39±0.61 mm, P< 0.001 and 0.77±0.09 mm versus 0.51±0.05 mm, P< 0.001, respectively). EFT was correlated with CIMT (r = 0.724, P < 0.001), duration of diabetes (r = 0.723, P < 0.001) and fasting plasma glucose level (r = 0.542, P < 0.001). Linear regression analysis showed that CIMT (β = 0.358, t = 3.658, P < 0.001) duration of diabetes (β = 0.324, t = 3.268, P = 0.001) and fasting plasma glucose level (β = 0.210, t = 3.302, P = 0.001) were found to be the independent predictors of EFT.Conclusion: The echocardiographic EFT was significantly higher in patients with T2DM; and it was well correlated with CIMT, duration of diabetes and fasting plasma glucose level as being the independent predictors of EFT.Asian Journal of Medical Sciences Vol.7(6) 2016 1-5
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