Invasive alien species are non-native exotic organisms which can disperse and destroy the biodiversity and change the ecosystem. The present study deals with the comprehensive list of invasive alien plants (IAPs) of Rourkela Steel City, Sundargarh, Odisha, with background information on family, habit, and nativity. A total of 165 invasive alien species under 132 genera and 59 families have been recorded. From the nativity study, among 25 geographic regions, the majority of invasive plants reported from American continent (62%) with 103 species. While in life form analysis, the herbs (114 species) are dominant, followed by trees (23 species), shrubs (22 species), climber (5 species), and undershrub (1 species). Ageratum conyzoides, Blumea lacera, Cassia alata, Lantana camara, Cassia tora, Parthenium hysterophorus, Xanthium sp., Datura sp., Cardamine scutata, Argemone mexicana, Grangea maderaspatana, Hyptis suaveolens, and Gnaphalium polycaulon are some noxious species found during the study. Parthenium hysterophorus is the highly noxious plant which is grown everywhere after Ageratum conyzoides and Lantana camara. Most of the invasive species are locally used for medicinal purposes as well as for food, fuel, and fodder purposes. A better planning and reporting of the spread of new plants in the area are needed for early identification and control of the invasive alien plant species in different seasons. Since the flora of Sundargarh districts has not been beneficially explored, this study will help in the compilation of flora of Sundargarh district and Rourkela in particular. Further studies will reveal the allelopathic effects on different agricultural crops as well as the different ethnobotanical values.