In the title 2:1 co-crystal, 2C4H5ClN4·C4H6O4 the complete succinic acid molecule is generated by a crystallographic centre of symmetry. In the crystal, pairwise O—H...N and N—H...O hydrogen bonds link the pyrimidine and succinic acid molecules, generating R 2 2(8) loops. The pyrimidine molecules are linked by pairwise N—H...N hydrogen bonds, again generating R 2 2(8) loops. Collectively, the hydrogen bonds link the components into corrugated (100) sheets. The Hirshfeld surface is presented.

Fused pyrimidine derivatives R 0515 4-(3-Methoxyphenyl)-1-substituted-4H-[1,2,4]triazolo[4,3-a]quinazolin-5-ones: New Class of H 1 -Antihistaminic Agents. -Compound (IXb), which is the most active antihistaminic agent, exhibits more potent activity compared to the standard drug chlorpheniramine maleate among negligible sedation and may serve as a lead molecule for further modification. -(ALAGARSAMY*, V.; SHARMA, H. K.; PARTHIBAN, P.; SINGH, J. C. H.; MURUGAN, S. T.; SOLOMON, V. R.; Pharmazie 64 (2009) 1, 5-9; Med. Chem. Res. Lab., MNR Coll. Pharm., Fasalwadi, Sangareddy 502 294, India; Eng.) -K. Woydowski

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