Objective: To assess the serum leptin and adiponectin in Iraqi children with asthma and compare it with healthy controls in Hilla province. Methods:Leptin and adiponectin were measured in 100 children; 60 newly diagnosed with asthma and 40 non-asthmatic children with a comparable age and sex were enrolled in this study. Asthmatic children subdivided into two groups; 30 patients in each group (obese and non-obese). The age of patients and control ranged between 2 and 12 years. The study was conducted in the Department of Biochemistry, College of Medicine, University of Babylon, leptin and adiponectin were estimated by enzyme-linked immunoassay, enzyme-linked immunosorbent assay technique.Results: An increase in leptin and decrease adiponectin levels in the obese group than in non-obese asthmatic and control groups, with significant difference (p<0.04) and (p<0.03), respectively. Conclusion:Among obese asthmatic Iraqi children, increase and decrease levels of leptin and adiponectin, respectively, indicate the significant association between adipokines and obesity in asthma.

A 35 females used low dose combination oral contraceptive were enrolled in addition to 20 age matched healthy females included as a healthy control group.PT was estimated in plasma of all subjects.It was found significantly prolonged PT in users when compared with nonusers,and the results indicated prolong PT in the first 2 years of drug used and the alteration of PT disappear with continuous used. The results demonstrated the effect of low dose combination oral contraceptives on PT.