Breast cancer is the most common malignancy in women in the UK with well-defined algorithms of management in place in the western world. Squamous cell carcinoma of the breast is a rare entity and as such knowledge about the pathophysiology, treatment and prognosis are still uncertain. The report describes an unusual case of squamous cell carcinoma arising in an area of Zuska's disease of the breast. It illustrates the heterogeneity of the imaging findings with review of the literature. Decisions on management should be taken on an individual basis with full discussion in the multidisciplinary team meetings where all facets of the case are considered.

Breast Cancer: Current ResearchBr ea s t C a n ce r: Curre nt R e se ar ch Khawaja et al., Breast Can Curr Res 2015, 1:1 Keywords: Breast conserving surgery; Oncoplastic breast surgery;Wide local excision; Breast cancer; Cosmesis IntroductionIn women with early stage unifocal breast cancer, breast conserving surgery followed by radiotherapy is the recommended choice. However, in some women, lesions are difficult to excise without the risk of cosmetic deformity or inadequate margin clearance. These women often present with large tumors in relatively small breasts requiring an excision of approximately 15% to 20% of the breast volume or more than 30% in large breasts. Another factor affecting poor cosmesis after breast conserving surgery is tumors located in aesthetically sensitive areas such as the central, medial, and inferior quadrants [1,2].In recent years, oncoplastic breast conserving surgery (OPS) has increased in popularity. OPS combines the principles of oncologic and plastic surgery techniques to gain oncologically and aesthetically pleasing results [3]. As these techniques become more accepted there is a demand for surgeons to become familiar with the indications and skills required to make oncoplastic surgery safe and effective [4].The choice between different oncoplastic techniques are determined mainly by the site of the tumor in the breast, tumor characteristics, extent of resection, breast characteristics (size, shape and glandular density), previous surgery, and the expectations and wishes of the patient [5].OPS can be classified into two main approaches according to the reconstruction technique used. Volume displacement techniques are applied to correct quadrantectomy defects in medium to large breasts [6]. They are of particular benefit to those patients who present with ptotic dense glandular breasts. The breast glandular tissue is advanced, rotated or transpositioned to fill the defect [7]. Since this may result in a smaller sized breast, contralateral surgery may be required. Conversely, AbstractBackground: The goal of breast conserving surgery is to achieve complete excision of the tumor with adequate surgical margins, while preserving the natural shape and appearance of the breast. This is a retrospective study which compared operative outcomes in oncoplastic (OPS; n=54) versus standard wide local excision (WLE; n=265) populations. A total of 319 consecutive patients were included in the study. The primary outcomes were the size of the tumor, weight of the specimen and margin clearance. The secondary outcomes were patient satisfaction, local recurrence rates and operative time.

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