Carvacrol (CAR), a naturally occurring phenolic monoterpene, has been shown to possess diverse biological activities. The present study was undertaken to evaluate the cardioprotective potential of CAR against myocardial ischemic damage in a rat model of acute myocardial infarction. CAR significantly diminished the infarct size and myocardial enzymes including creatine kinase (CK), the MB isoenzyme of creatine kinase (CK-MB), lactate dehydrogenase (LDH) and cardiac troponin T (cTnT). Reduced level of malondialdehyde (MDA), obviously elevated activities of superoxide dismutase (SOD) and non-enzymatic scavenger glutathione (GSH) as well as glutathione peroxidase (GSH-PX) were also found in CAR-treated groups. Treatment with CAR remarkably inhibited the protein expressions of caspase-3 and Bax, but increased the level of Bcl-2 protein in infarcted rats by Western blot analysis. The finding suggests that the cardioprotection of CAR associate with its anti-oxidative and anti-apoptotic properties in acute myocardial infarction of rats.
In recent years, with the rapid development of colorectal surgery technology and laparoscopic instruments, laparoscopic radical resection of colorectal cancer has been widely used. Although laparoscopic surgery has the characteristics of small trauma, less blood loss, less hospitalization days, and low incidence of adverse reactions such as incision infection, it is still inevitable to have different degrees of gastrointestinal dysfunction after surgery. This paper mainly studies the recovery nursing of gastrointestinal peristalsis after abdominal mirror in rectal cancer patients based on intelligent electronic medicine. In this paper, an intelligent medical monitoring system is designed for the posterior care of rectal cancer patients with abdominal mirror image, which can realize the collection and transmission of wireless sign parameters of postoperative rectal cancer patients and improve the efficiency of postoperative monitoring in medical work. All parameter data are sent to the Lora base station in real time via Lora wireless communication, which is then uploaded to the medical monitoring platform. The experimental results showed that the first postoperative exhaust time of the treatment group using the intelligent medical monitoring system was significantly shortened, and the difference was statistically significant ( P < 0.05 ). The first defecation time was shortened, and the difference was statistically significant ( P < 0.05 ). The recovery time of total fluid diet was shortened, and the difference was statistically significant ( P < 0.05 ). The above results indicate that the intelligent medical monitoring device designed in this paper has positive significance for improving the work efficiency of the hospital, the clinical experience of patients after abdominal mirror surgery for rectal cancer, and the real-time monitoring of signs of patients in intensive care.
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