CDT for acute PAO with alfimeprase was as safe as placebo. However, alfimeprase was no more effective than placebo in increasing 30-day surgery-free survival. The surprising effectiveness of placebo alone demonstrates that the inclusion of a placebo arm is essential to the design of future lytic trials.
Reports of fatality following carbon dioxide digital subtraction angiography (CO 2-DSA) have raised concerns regarding its safety. This study reviews the safety of CO 2-DSA.
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