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Background:In the process pregnancy-postpartum, the role of the husband is very important and necessary. It is highly expected for the husbands to accompany their wives, so that their wives can have healthy pregnancy which is later able to give birth a healthy baby and the mothers can survive. Objectives: The purpose of this study is to find out the effect of husband's knowledge regarding Antenatal Care (ANC) and Early High-Risk Detection, husband behavior in the pregnancy-postpartum care with reproductive health problems experienced by wife and to determine which variable that has the greatest effect among the three variables. Metohdes: This research is an analytical observation, carried out in the working area of Tinggede Health Center which includes 3 villages namely Sunju, Tinggede and South Tinggede the research target is all husbands who have pregnant wife (second pregnancy) and have children under two years old with a total of 180 husbands. The survey was carried out on 180 husbands. Data collection is carried out through interviews, observations and FGDs. Data analysis technique with Chi Square value test (p <0.05) Results: The results showed that the level of husband's knowledge about Antenatal Care and early detection of high risk was low, 58.88% and 56.66%, respectively. Husband behavior in pregnancy care was also categorized as less healthy/bad, i.e., 55.55%, and the prevalence of wife's respondents who experienced reproductive health problems was 57.7%. Husband's knowledge about ANC, early detection of high-risk pregnancy, and husband behavior in pregnancy care had a significant relationship to reproductive health problems (p<0.05). The highest frequency of husband's participation in the pregnancy-postpartum care is making referrals to the healthcare facilities by 79%, Husband behavior in pregnancy care has the greatest effect on maternal reproductive health problems with a P value = 0.001. Conclusion: It can be concluded that the husband's knowledge regarding ANC and early detection of pregnancy and postpartum period has an effect on maternal reproductive health in Sigi Regency, Central Sulawesi. It's expected that the development of models for improving husband's Information, Advocacy and Communication (IAC) of reproductive health could be a preventive effort in improving women's reproductive health.

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