Microcirculation in a subject can be examined and pathological changes can be assessed by utilizing capillaroscopy, which is a very safe, convenient and non-invasive approach. Using a microscope, doctors view the capillaries by looking through nailfold epidermis. Nailfold anatomy is ideal to evaluate the microcirculation and detect various diseases caused by vascular damages. Rheumatologists evaluate systemic diseases which involve damage in vasculature, by analyzing the red blood cells within the capillaries. Sometimes, capillary morphology may be useful as an early indicator while, severity of damage in capillary architecture may indicate internal organ involvement. Thus, in a capillaroscopic assessment, the doctor examines modifications in morphological and functional aspects of capillaries. These comprise of capillary diameter, visibility, distribution, length, microhemorrhages, blood flow and density. In this paper, a novel object detection algorithm is proposed based on deep learning architectures for detecting and locating various capillary loops in the nailfold region. Various characteristic features are extracted from the capillaries through image processing algorithms and in turn an attempt is made to differentiate between images of diseased subjects and healthy controls.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.