A total of 244 samples of cereals (wheat flour, rice, and maize), pulses (arhar, moong, gram, lentil, and black gram), spices (turmeric, chili, coriander, and black pepper), vegetables (potato, onion, spinach, cabbage, brinjal, and tomato), fruits (mango, guava, apple, and grape), milk, butter, DeshI ghee, and edible oils (vegetable, mustard, groundnut, and sesame) collected from different cities of Northern Province (Utter Pradesh) were analyzed by gas liquid chromatography for the presence of organochlorine pesticide residues. Residues of hexachlorocyclohexane (HCH) and 2,2-bls(p-chlorophenyl)- 1,1,1-trlchloroethane (DDT) were detected In about 85% of the total samples of cereals, spices, milk, butter, DeshI ghee, and edible oils analyzed in the present study. However, the residue levels were either very small (<0.06 ppm) or not detected at all In pulses, vegetables, and fruits as compared with very high concentrations In wheat flour (4.42 and 0.12 ppm), butter (1.19 and 4.85 ppm), mustard oil (1.26 and 2.42 ppm), DeshI ghee (1.10 and 3.84 ppm), vegetable oil (1.02 and 0.59 ppm), groundnut oil (0.51 and 1.49 ppm), and chili (0.48 and 1.92 ppm). The levels of HCH and DDT residues detected in rice, maize, turmeric, coriander, black pepper, and all the vegetables and fruits were also lower than those found In wheat flour, oil, and fat samples analyzed In the present study. These findings suggest that a restricted and controlled use of such persistent pesticides may be useful for decreasing their contamination levels In different food Items.

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Several 2‐aryl substituted thiosemicarbazido‐4‐methyl‐6‐methoxyquinolines and 2‐aryl substituted semi‐carbazido 4‐methyl‐6‐methoxyquinolines were synthesized and evaluated for their antimalarial activity in mice infected with Plasmodium berghei. Two of these substituted quinolines were found to exhibit 50% clearance in a dose of 500 mg./kg. administered intraperitoneally for 5 days.