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KW-1062 120 mg was intramuscularly administered to five healthy adult volunteers. After 30 minutes, they presented 7.28 ig/m1 of peak blood concentration. Mean recovery rate in urine was 84.5% for 24 hours.When administered to three healthy adult volunteers every 12 hours for 5 days, no accumulation of the drug in blood was observed.Overall clinical efficacy rate of KW-1062 was 71.6% in the treatment of 95 cases with respiratory tract infections. 72.2% of 36 patients with chronic bronchitis or panbronchitis and 69.0% of 42 patients with pneumonia or bronchopneumonia responded well to the drug.Side effects were encountered with 11 cases (9.8%). The results obtained suggest that the drug is useful in the treatment of respiratory tract infections due to gram-negative bacilli.

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