ARTICLE INFO ABSTRACTBackground: Alcohol consumption leads to abnormalities in various cell lines. However the association between haematological abnormalities and complications in alcohol dependence syndrome have not been established fully Aim: To evaluate the frequency and spectrum of abnormalities in blood indices and blood cytology in patients with Alcohol dependence syndrome Methodology: Population for study consisted of 65 consecutive patients diagnosed to have Alcohol Dependence Syndrome admitted in De-addiction ward. Patients were sub grouped based on the complications they developed during withdrawal period. Thorough clinical examination was done and relevant blood investigations were done and interpreted with the help of a clinical pathologist. Results: High statistical significance of AUDIT score in diagnosis of alcohol dependence and withdrawal complications was found(p=0.001). Majority of patients were in the age group of 31-40 years.RBC count and platelet count was found to be significantly reduced in alcohol dependence syndrome with complications(p<0.05). Total leucocyte count variation was found to be nil significant (p>0.05). High prevalence of macrocytosis (15.4%), eosinophilia (15.4%), thrombocytopenia (13.8%), lymphocytosis (10.8%) were found in alcohol dependence syndrome and higher values were observed in complications. Conclusion: Detailed evaluation of blood cytology and blood indices should be done at an early stage during management of Alcohol dependence syndrome along with AUDIT to detect patients who can develop complications.

Background: Alcohol dependence syndrome is associated with many health problems especially skin change. There are various psychosocial implications in patients who have comorbid skin disorders. Nutritional deficiency due to malabsorption in alcohol dependence syndrome leads to nonhealing skin lesions. This study aimed to evaluate the frequency and spectrum of dermatological disorders in patients with alcohol dependence syndrome. Materials and methods: Population for the study consisted of patients diagnosed of alcohol dependence syndrome admitted in deaddiction ward. Thirty consecutive patients with diagnosis of alcohol dependence syndrome formed the sample of the study. Thorough clinical examination was done for diagnosis of dermatological disorders with the help of a dermatologist. Results: Majority of patients attending were in the age group of 31-40 years. Most of them were Christians, educated up to primary from a nuclear population. Higher significance was found in patients in joint families and with an income of less than 5,000. The findings of this study revealed higher prevalence of tinea versicolor (13%), seborrheic dermatitis (11%), and scabies (2%) in patients with alcohol dependence syndrome.