The present study was designed to manage the feeling of inferiority & insecurity of HIV+ /AIDS patients through Yagya therapy. HIV+/AIDS is a type of immunodeficiency which is caused by the retrovirus HIV (Human Immunodeficiency Virus). Eighty diagnosed HIV+/AIDS subjects in the range of 12 to 40 years were selected form Haridwar, Dehradun, and Roorkee districts on the basis of score obtained on the Inferiority and Insecurity Questionnaire (Pati, 1976). These subjects were assigned randomly to two conditions namely, control (N=40, 20 males and 20 females) and experimental (N=40, 20 males and 20 females). The subjects in the experimental group were only exposed to Yayga therapy practices about one hour daily for six months. A between group design was used in the present study and obtained data were statistically analyzed through t-test. The finding reveals that Yagya therapy significantly reduces the levels of inferiority and insecurity feeling of patients. Conclusion: Yagya therapy is an effective therapy for managing inferiority & insecurity feeling of HIV+ patients.