30 -34°N, 74 -78°E). The influence of meteorological parameters viz. temperature, rainfall, relative humidity and wind velocity on radon concentration was qualitatively evaluated. The radon exhalation showed positive correlation with temperature, rainfall, relative humidity and negative correlation with wind velocity. Both positive and negative radon anomalies were recorded. The study reveals the precursory nature of radon anomalies and their correlation with microseismic events in 62% of the cases but prediction of earthquakes is yet a remote possibility. From the analysis it has been found that radon anomaly is not only influenced by seismic parameters but also by meteorological parameters and the nature of carrier gases/fluids. To learn more about the phenomenon, simultaneous recording of various gases (He, CO 2 , CH 4 ) and meteorologi- TAO, Vol. 16, No. 4, October 2005 776 cal parameters, together with multiple continuous measurements of radon have been suggested.
Objective: To examine the ability of three different proteinuria assessment methods (urinary dipstick, spot urine protein:creatinine ratio [Pr/Cr], and 24-hour urine collection) to predict adverse pregnancy outcomes
Methods:We performed a prospective multicentre cohort study, PIERS (Preeclampsia Integrated Estimate of RiSk), in seven academic tertiary maternity centres practising expectant management of preeclampsia remote from term in Canada, New Zealand, and Australia Eligible women were those admitted with preeclampsia who had at least one antenatal proteinuria assessment by urinary dipstick, spot urine Pr/Cr ratio, and/or 24-hour urine collection Proteinuria assessment was done either visually at the bedside (by dipstick) or by hospital clinical laboratories for spot urine Pr/Cr and 24-hour urine collection We calculated receiver operating characteristic area under the curve (95% CI) for each proteinuria method and each of the combined adverse maternal outcomes (within 48 hours) or adverse perinatal outcomes (at any time) Models with AUC ≥ 070 were considered of interest Analyses were run for all women who had each type of proteinuria assessment and for a cohort of women ("ALL measures") who had all three proteinuria assessmentsResults: More women were proteinuric by urinary dipstick (≥ 2+, 614%) than by spot urine Pr/Cr (≥ 30g/mol, 504%) or 24-hour urine collection (≥ 03g/d, 347%) Each proteinuria measure evaluated had some discriminative power, and dipstick proteinuria (categorical) performed as well as other methods No single method was predictive of adverse perinatal outcome
Conclusion:The measured amount of proteinuria should not be used in isolation for decision-making in women with preeclampsia Dipstick proteinuria performs as well as other methods of assessing proteinuria for prediction of adverse events
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