In the field of cryptography, the substitution box (Sbox) becomes the most widely used ciphers. The process of creating new and powerful S-boxes never end. Various methods are proposed to make the S-box becomes strongest and hard to attack. The strength or weakness of S-box will be determined through the analysis of S-box properties. However, the analysis of the properties of the S-box in block ciphers is still lacking because there is no specific guidelines and technique based on Sbox properties. Hence, the cipher is easier to attack by an adversary if the S-box properties are not robust. The purpose of this paper is to describe and review of the S-box properties in block ciphers. As a result, for future work, a new model for analysis S-box properties will be proposed. The model can be used to analysis the properties to determine the strength and weakness of any S-boxes.

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In data encryption, the security of the algorithm is measured based on Shannon’s confusion and diffusion properties. This paper identifies the correspondences and highlights the essential computation elements on the basis of randomness and non-linearity of immune systems. These systems can be applied in symmetric encryption algorithm that satisfies the properties in designing a new symmetric encryption block cipher. The proposed symmetric encryption block cipher called the 3D-AES uses components of the Advanced Encryption Standard (AES) symmetric encryption block cipher and the new core components based on immune systems approaches. To ensure adequate high security of the systems in the world of information technology, the laboratory experiment results are presented and analyzed. They show that the randomness and non-linearity of the output in the 3D-AES symmetric encryption block cipher are comparable to the AES symmetric encryption block cipher.