Atopic dermatitis is a commonly presenting chronic inflammatory skin disease in children. It is triggered by a variety of irritative and allergic factors. Both genetics and environmental factors play a significant role in development of atopic dermatitis. Atopic Dermatitis may have association with other atopic diseases (IgE mediated) like bronchial asthma, urticaria, allergic rhinitis, food allergies etc. It affects children (10-20%) as well as adults (1-3%), the incidence being highest in early infancy and childhood. There are many homoeopathic medicines that are very effective in management of atopic dermatitis. The lesser indicated homoeopathic medicines for AD include Chrysarobinum, Croton Tig, Rhus venenata, Copaiva, Oleander, Arsenicum iodatum, Primula obconica, Mercurius dulcis and Kali arsenicum.