Riluzole specifically relieves visceral hypersensitivity and is proved to be superior to current treatments in IBS patients. It appears a lead remedy based on glutamate transporter mechanisms in visceral hypersensititvity.

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Severe Acute Respiratory Syndrome Coronavirus-2 is the causative agent of Coronavirus Disease 2019 named by the World Health Organization (WHO) on 11th February 2020 and declared pandemic on March bears mild symptoms like fever, fatigue, dry cough to critical conditions like chronic respiratory disease leads to death. There are many misconceptions and vast internet information manipulating brains of the victimized society, which sow anxiety in people regarding this syndrome, and to provide adequate and accurate information literature reviews are must. This review article intends to deliver the current valuable information regarding the evolution, virology, and mode of transmission and epidemiology of SARS-CoV-2 along with the clinical management describing specific effective treatments, therapeutics, and vaccines through considering the clinical features of COVID-19. Several preventive measures, such as quarantine, self-isolation, and social distancing, are also elaborated. For the administration of this worldwide pandemic, the multifactorial assortment of endorsed examinations on each of these sections of COVID-19 inside this assessment empowers explanation and transparency on the existing eminence.