Liver homing of clinical grade Tregs after therapeutic infusion in patients with autoimmune hepatitis Tregs suppress proliferation and cytokine production of T effector cells & prevent autoimmunity Autologous Tregs home to inflamed autoimmune livers after infusion without side effects Autoimmune hepatitis patients Tregs express CXCR3 chemokine receptor and are functional Highlights • Tregs from patients with autoimmune hepatitis are suppressive, possess functional markers CD39 and CTLA-4, and express CXCR3. • Treg infusion in autoimmune liver disease is safe without any side effects. • 22-44% of infused Tregs home to and were retained in the livers of patients with autoimmune hepatitis for up to 72 hours.