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Measurements/Results: Of the 55 patients, at least one SLN was identified in 53 patients (96.4%), and bilateral SLNs were identified in 41 patients (77.3%). A total of 390 SLN was harvested, and the average SLN count of each pelvis was 4.0, distributed in the iliac vascular lymphatic region, obturator region and paracervical region. After pathological examination of these 53 patients, 12 showed lymph node metastasis with 10 occurring in the detected SLNs and the other two in the non-SLNs. The new method showed accuracy of 96.3% (51/53), a sensitivity of 80% (10/12), a false negative rate of 16.7% (2/12), and negative predictive value of 95.4% (41/43). Adverse reactions were not observed in any cases. Conclusions: With high overall and bilateral detection rates, carbon nanoparticles provide a feasible and efficient method in SLN mapping of cervical cancer.

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