Toe synthesis of new unsymmetrical A,B porphyrin, 5,10,15-tri(4-methoxyphenyl)-20-(4-chlorophenyl)-21H, 23H-porphyrin, 1, and its Zinc(II) complex, 5, 1 O, 15-tri( 4-methoxyphenyl)-20-( 4-chlorophenyl)-21, 23- Zinc(II)-porphine, l, was accomplished using both conventional and "one pot" solventless microwave assisted methods with interesting comparative results. The obtained molecules were characterized by 'H NMR, UV-Vis and MS. These molecules are considered to represent new compounds with potential application as photosensitizers in photodynamic therapy.

The monomer 3-hexylthiophen-2,5-dicarboxaldehyde was synthetized from precursor 3-hexylthiophene by VilsmeierHaack reaction. Three p-type semiconductor polymers (PHT-P, PHT-B and PHT-H) were synthetized by aldol condensation from this monomer with three different ketones (propanone, butanone and hexanone). Three composites were created by adding PbS/ZnS nanoparticles to these polymers. Light absorption increased to the red from polymers to composites. Electrical conductivity increased from 10% S/cm in polymers to 10! S/cm in composites.

The asymmetric unit of the title compound C11H16N,05 , contains one molecule of the compound (L3) (1,3-bis(2-nitrobenzylideneamino )propan-2-ol). The molecule shows a chiral C atom but the absolute structure was not possible to be determined by X-ray diffraction. The molecule shows intermolecular hydrogen bonding involving the hydroxy group and an imine nitrogen atom of a symmetry related molecule. The molecular distribution shows weak interactions between oxygen atoms of the nitro groups and two different C-H groups of benzene rings. The extended weak H bond formation, using the N02 groups, probably gives a more stable crystal structure. The molecule represents a precursor of a polyaza macrocylic ligands.

SnIV complexes of the series of bulky amines have been reported by electrochemical oxidation (3 h) of a tin anode in a cell containing methanol solution of the corresponding bulky amine. All were full characterized by 1H and 13C-NMR, IR, and high resolution mass spectrometry. However, all were not enough soluble in organic solvent in order to record its 119Sn-NMR spectra, this unusual behavior was attributed to the polymeric association thought intermolecular coordination OSn.

En este trabajo se describe la síntesis de nuevos u-amidofosfonatos, los cuales fueron preparados a partir de la (S)-fenilalanina, la 2-metil-5- nitroanilina y el 2-arninofenol. Las rutas sintéticas empleadas para la preparación de los compuestos presentan buenos rendimientos quhnicos. Las moléculas obtenidas fueron caracterizadas por RMN 1H y EM, fueron utilizadas para sintetizar un complejo de Sn(IV) y evaluar su efecto tóxico sobreArtemia Salina. Aún cuando se puede sintetizar exitosamente el complejo de estaño, las pruebas biológicas y su posible aplicación terapéutica está limitada por la alta inestabilidad a temperatura ambiente. El ensayo en A. salina permitió realizar untamizaje adecuado descartando diversos compuestos y focalizando la atención en los que tuvieron mejor capacidad tóxica. Los amidofosfonatos 12 y 13 muestran datos prometedores, por lo cual se proponen como candidatos para estudiar su actividad sobre cultivos de células de origen neoplásico y sobre células normales.