Background Around 80% of human population in the world relies on herbal or phytomedicines for their primary health care needs. The treatment of many diseases and disorders with phytomedicines is considered and observed as very safe with no or minimal side effects. Many medicinal plants and their preparations are practised at home as remedies for treating and preventing various diseases and disorders. For example, medicinal plants and their crude parts such as tulsi, neem, turmeric and ginger are used to cure or treat several common ailments, out of which Curcuma zedoaria Rosc commonly known as white turmeric is one of the important crude drugs belonging to Zingiberaceae family and genus Curcuma. Traditionally, it has been reported to possess many biological activities been used for many therapeutic actions due to the presence of wide range of phytoconstituents in it. The main objectives of the present work are to carry out extensive review on its chemical, pharmacological and biological activities of plant. Main body In the present review article, extensive data on its chemical, pharmacological and biological activities have been collected from various online sources including indexing sites such as Web of Science, Scopus, PubMed and Research Gate and presented. Various articles published in indexed journals and other databases have been collected and reviewed systematically. Conclusion The present review investigation is very much helpful for researchers and readers to collectively have valuable information on chemistry, pharmacology and biological effects of Curcuma zedoaria Rosc. The present investigation concludes that the white turmeric is found to possess complex range of phytoconstituents such as curcumin, ethyl p-methoxycinnamate, β-turmerone, β-eudesmol, zingiberene, dihydrocurcumin, furanodiene, α-phellandrene, 1–8 cineole, β-elemense and germacrone. Due to the presence of wide range of phytoconstituents, plants have been reported for its diverse biological activities.

Background Herbal medicines and their preparations have been mostly used since from thousands of years in all developing and developed countries in the primary health care of society and community. Flavonoids are the class of polyphenolic compounds, which are mainly distributed throughout the plant kingdom. Quercetin is a flavonoid which shows major pharmacological activities and effectively used for the management and treatment of various diseases and disorders. Many herbal medicines and their formulations containing Quercetin are available in market and hence quality control of Quercetin in is very important and essential in manufacturing industries Main body of the abstract We have reviewed various scientific research published on quality control analysis and standardization of Quercetin in its isolated form, extract or any other herbal or polyherbal preparation. We have mainly focused on the spectroscopic and chromatographic methods for qualitative and quantitative analysis of Quercetin and they were comprehensively presented in the present review work. Short conclusion The present review concludes that the spectroscopic and chromatographic methods play great role in the quality control and standardization of Quercetin in its isolated form, extract and in its herbal and polyherbal preparation.

Background Heart Study has been operating for more than 40 years, and throughout that time it has found a number of risk variables that interact negatively to have an overall negative effect on cardiovascular disease (CVD) with an estimated 17.9 million deaths per year, CVD is the world's leading cause of death. Main body In the current study, we present spectrophotometric, chromatographic analysis and bioanalysis methods for qualitative and quantitative evaluation of 15 drugs, including small and large molecules, that the U.S. FDA approved between 2015 and June 2020 to treat CVD’s and in the current review work, they were presented. Short conclusion The review's conclusion is that spectroscopic, chromatographic and bioanalysis methods play important role in quality control and standardization of recently approved drugs from 2015 to 2020 for treating CVD’s in its bulk, pharmaceutical dosage form, synthetic mixture or human/rat plasma.