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<p class="MsoNormal"> <span lang="EN-US">Pulmonary embolism (PE) is a clinical entity with high mortality rate and therefore rapid diagnosis is necessary. For this purpose many diagnostic strategies have been developed for avoiding or necessitating further investigations. The hallmark of these strategies is assessing the pretest clinic probability of PE. In this study, the effectiveness of Wells, <st1:city w:st="on"><st1:place w:st="on">Geneva</st1:place></st1:city> and Kline methods were investigated in a university hospital emergency department. 74 patients were enrolled in this study. The inter-group differences in scoring systems were significant for Wells and Kline but non-significant for <st1:city w:st="on"><st1:place w:st="on">Geneva</st1:place></st1:city> method. The diagnosis of PE was correlated with Wells and Kline system but <st1:city w:st="on"><st1:place w:st="on">Geneva</st1:place></st1:city> system lacked it. The Receiver Operating Characteristic analyses was performed for comparing the pretest clinical probability scoring sys</span><span lang="EN-US">tems and the greatest area under the curve was found in Wells system. Wells method seems more useful compared to <st1:city w:st="on"><st1:place w:st="on">Geneva</st1:place></st1:city> and Kline methods particularly in emergency department.</span><span lang="EN-US"><o:p></o:p></span> </p>

Introduction: There may be some cardiac and non-cardiac side effects of propafenone hydrochloride, which is a class IC antiarrhythmic agent used for medical cardioversion in atrial fibrillation and atrial flutter. Case Report: Propafenone hydrochloride (600 mg) was orally administered to a 74-year-old patient with tachycardia due to new-onset atrial fibrillation with rapid ventricular response. After 30 min, sinus bradycardia in response to atropine, swelling and numbness in the tongue, slurred speech, blurred vision, diplopia, spasm and contradiction at the right arm and leg, drowsiness, and visual hallucinations lasting for 24 h developed. The patient recovered without any sequel and was discharged from the coronary intensive care unit. Conclusion: Although propafenone hydrochloride is known to be safe at therapeutic doses, various possible multiple side effects should be considered.