An assessment of soil sensitivity was carried out regarding the soil suitability for wastewater reuse. This was done based on digital soil maps joined with spatial data on soil properties using Geographic Information Systems (GIS). Six major risks of primarily agricultural significance were defined in close collaboration with regional experts. The changes in particular soil and groundwater properties as a result of irrigation with low water quality were evaluated and discussed. Based on the local soil parameters, the specific sensitivity and suitability grades were assessed for the respective soil unit concerning irrigation with treated wastewater (TWW) using standard and specially developed methods. In OPEN ACCESSWater 2011, 3 1093 conclusion, with regard to soil suitability criteria, sensitivity and suitability maps, including the aggregated total sensitivity, were presented for supporting sustainable irrigation practices.