Preeclampsia is one of the most important pregnancy disorder, diagnosed with hypertension and proteinuria. It is the leading cause of fetal and maternal morbidity and mortality. This cross-sectional study was conducted in 100 pregnant women, of them, 50 were diagnosed cases of preeclampsia and 50 were normal pregnant women attended in the Gynaecology and Obstetrics department of Dhaka Medical College Hospital, Dhaka, during July 2016 to June 2017. Five ml fasting blood sample was collected and was analysed for triglyceride using standard enzymatic method. Mean value of triglyceride was compared between two groups by student unpaired t-test and the triglyceride level was correlated with systolic, diastolic blood pressure and urine albumin in preeclamptic patient was correlated by Pearson's correlation coefficient test. A p-value was considered to be statistically significant at 0.05 at 95% confidence interval. Statistically significant difference of serum triglyceride level was found in preeclamptic women and normal pregnant women (p<0.05). The level was 248.90±31.36 mg/dl in preeclampsia and 197.00±27.04 mg/dl in normal pregnant women respectively. Serum triglyceride was positively correlated with systolic, diastolic blood pressure and urine albumin in preeclamptic women. Faridpur Med. Coll. J. Jul 2019;14(2): 82-85

Eclampsia has a high prevalence in our country with a high mortality rate. Eclampsia is uniquely a disease of pregnancy and regardless of gestational age. It is recognized that termination of pregnancy is the only definitive care of pathophysiological event in eclampsia. This study was done to observe fetomaternal outcome in Lower Uterine Segment Caesarean Section (LUCS) and vaginal delivery in eclamptic patient. This cross sectional analytical study was carried out in eclampsia department of Obst and Gyane in Dhaka Medical College Hospital from July 2016 to June 2018. A uniform protocol was followed in all cases to have appropriate history, physical findings and laboratory investigations. In this study 98.0% patients were conscious on admission in group I and 96.0% in group II. This study showed significant difference in recurrence of convulsion after delivery between two groups. Recurrence of convulsion was 30% in vaginal delivery group and 6% in the cesarean section group. Total complications were found in 46.0% and 16.0% patients in group I and group II respectively in this study. The difference was statistically significant (p<0.05) between two groups. In this study PPH was the most common complication in both the groups. Abruptio placenta was found more common among the vaginal delivery group. On the other hand, electrolyte imbalance was found more in cesarean section group. Maternal death was only 2% and 1% in group I and group II respectively. In this study live birth was found 64.0% and 79% in group I and group II respectively. Asphyxia was more in neonates in group I than group II which was statistically significant. Referral of asphyxiated babies to NICU was found 63.0% and 56.0% in group I and II respectively. The difference was statistically not significant between two groups. Faridpur Med. Coll. J. Jan 2020;15(1): 16-20

Among the common disorders of pregnancy, Pre-eclampsia is important one which causes significant maternal and perinatal morbidity and mortality. Its incidence is still high in the developing countries. The triad of high blood pressure, edema and albuminuria is neither specific nor sensitive enough; therefore, a reliable biochemical marker is needed to solve the problem. C-reactive protein(CRP), a marker of tissue damage and inflammation, is elevated in serum in overt preeclampsia. The present study is aimed to explore the association of high maternal serum C-reactive protein (CRP) level with preeclampsia and correlation with the severity of pre-eclamptic process. A total of 60 pregnant women constituting 30 pre-eclamptic (case) and 30 normal (control) pregnant women in the third trimester were enrolled in this study. Both the groups were matched for their age, parity and other baseline characteristics. More than three quarters (76.70%) of the case group exhibited raised serum CRP, which was 20% in control group (p=0.001). CRP was elevated about 13 fold higher than that in the normal pregnant women. The mean systolic and diastolic blood pressure were significantly higher in case group (154±12 mm of Hg) vs (107±7 mm of Hg) in control group (p<_0.001) and serum level of CRP bears linear relationship with both systolic and diastolic blood pressures. Preeclamptic women with higher serum CRP level were at a significantly (p<0.001) lower gestational age than control. Twenty two (73.30%) cases had gestational age <37 weeks (p=0.302) and 66.70% control group had gestational age > 37 weeks. The hypothesis of the study was supported by the study findings that maternal CRP concentration was higher in women with preeclampsia and was correlated with disease progression as evidenced by the investigative analysis. Faridpur Med. Coll. J. Jan 2020;15(2): 58-61

Postpartum Acute Kidney Injury (AKI) is one of the serious complications of pregnancy and is associated with high mortality and morbidity. Although Postpartum AKI has decreased markedly in developed countries in the last 50 years, but it is a challenging health problem in pregnant women, specially in the developing countries like Bangladesh. Aim of this study was to determine the contributing factors and outcome of postpartum AKI. This observational study was conducted in the department of nephrology, Faridpur Medical College Hospital from January 2018 to December 2019. During that study period thirty two patients with postpartum AKI were admitted in the above mentioned department. Demographic, clinical and laboratory data of those patients were recorded. Mean age of patients was 25.3 ± 4.2 years, and the 72% patients underwent cesarean section. Oliguria was the main presentation (91%). Puerperal sepsis (38%), postpartum hemorrhage (22%), and Eclampsia (16%) were the common contributing factors. Hemodialysis was required for most of the patients (75%). Therefore early diagnosis, identification and treatment of cause, timely initiation of renal replacement therapy is mandatory. Faridpur Med. Coll. J. 2020;15(2): 62-64