Introduction Possibility of a causal influence of emotional stress, on the course of various skin diseases, has been postulated. However, it is still inconclusive about the role of stressful life events in acne. In this background, the present study was carried out to know its role in acne. Methods Consecutive one hundred patients who were diagnosed with acne vulgaris in the age group of 12 to 45 years were included. Age and sex matched controls were taken. A semistructured proforma was used to collect sociodemographic details. Stressful life events were assessed using presumptive stressful life event scale. Anxiety was evaluated using Hamilton Anxiety Rating scale and Depression by Hamilton Depression Rating Scale. Results There was no difference in total stressful life events in past one year between patients and controls. The undesirable life event was present in 65 patients and 50 controls, this difference was statistically significant. Getting married or appearing for exams were the most common stressful life event in patients. Forty patients had comorbid psychiatric illness whereas in controls comorbidity was in 24 and this difference was statistically significant. Discussion The undesirable stressful life events and psychiatric comorbidity were more in acne patients than in controls.

Background and Aim: In Asian countries, child bearing is a social obligation. Experience of infertility profoundly affects the personal well-being of women. Women with infertility are at a higher risk of anxiety, depression, and Intimate partner violence (IPV). In this background the present study was carried out to determine IPV and psychiatric comorbidity in women with infertility. Methods: Hundred consecutive women with primary infertility in the age group of 18 years to 45 years were included in the study. Psychiatric diagnosis was made according to DSM-5. Hamilton Anxiety Rating Scale (HAM-A) and Hamilton Depression Rating Scale (HAM-D) were used to assess the severity of the anxiety and depressive symptoms. IPV was assessed using WHO violence against women instrument. Results: The mean age of the 100 women was 26.73 ± 4.23 years, duration of marriage was 7.11 ± 4.177 years and duration of infertility treatment in years was 5.56 ± 3.89. The prevalence of IPV among patients was 50% and psychiatric comorbidity was 46%. When we compared the women who experienced IPV and who did not, the prevalence of anxiety disorder and depressive disorder was high among IPV group. Anxiety, depressive scores in HAM A, HAM D were higher in IPV group compared to the other group and was statistically significant. Conclusion: A significant number of women who had infertility reported IPV. This emphasizes the importance of screening for IPV in these women. It is observed that women with IPV had higher psychiatric comorbidity and may require psychotherapeutic intervention.

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Introduction: Depression and anxiety disorder are the common mental disorders. Serotonin ) is a well-established neurotransmitter in the central nervous system (CNS). It has a role in the anxiety, depression, appetite, motor, cognitive and autonomic functions, platelet aggregation and regulation of vascular tone. As the CNS is difficult to access, peripheral platelet models are widely used as the indicators of central 5-HT metabolism; moreover, they are known to reflect central serotonergic function. Mean platelet volume (MPV) is contemplated as the marker of platelet function. It is a measure of platelet size and a good indicator of platelet activity. In this backdrop the current study was carried out to evaluate the MPV in depression and anxiety disorders. Methods: Consecutive 90 depressive disorder patients, 76 anxiety disorder patients, diagnosed according to DSM 5 criteria and 49 healthy control subjects were selected for the study. Hamilton

We report a case of a brief psychotic disorder with type I Arnold-Chiari malformation and agenesis of the corpus callosum which was detected on a magnetic resonance imaging (MRI) scan. The patient was started on antipsychotics and underwent decompression surgery. He is on regular follow-up and returned to normal daily life within a few weeks. The antipsychotics were tapered and eventually stopped, and the patient is maintaining well in the follow-up. With improved neuroimaging techniques reporting brain morphological abnormalities in psychiatric patients has increased and we suggest that a neuroimaging investigation is valuable in psychotic illness. Arnold-Chiari malformation, agenesis of the corpus callosum, brief psychotic disorder