Introduction: The thyroglossal duct cyst (TDC, also known as the thyroglossal tract remnant, or TTR) is a well-known developmental anomaly that affects roughly 7% of the population.  It often manifests as a movable, painless lump. Objectives: to report our 2 years of clinical experience with thyroglossal cysts in terms of clinical aspects and surgical findings. Materials and methods: This study was conducted in Department of General Surgery, MKCG Medical College and Hospital, Berhampur over a period of 24 months from July 2019- June 2021. Results: The majority (72.72%) were under the age of fifteen. Patients aged 16 -30 years made about 24.24% of the patient population. Males made up 63.63 % of the population, while females made up 36.36%. 88% of patients had neck swelling when they arrived. 15.15% of patients exhibited erythema/redness over swelling, and 18.18% felt tenderness. 15.15% of patients at presentation had painful swelling and deglutination. 18.8% of patients reported having experienced recurrent neck swelling in the previous two years, while 12.12 % only had recurring discharge from the midline neck.

Background: Hypoxic ischemic encephalopathy (HIE) refers to the CNS dysfunction associated with Perinatal Asphyxia (PA) which is an important causes of permanent damage to CNS tissue. MRI imaging methods attributes to better understanding of pathological events and disease progression that may provide decision regarding intervention.  MRI has a higher sensitivity and is extremely valuable in assessing the extent of hypoxic-ischemic brain damage during the early postnatal period and later infancy. It is also more specific which clearly differentiates fluid filled cavities, oedema, gliosis and hemorrhage. On this background this study was undertaken to evaluate the MRI changes of all grades of HIE patients. They were also followed up at different time intervals for upto 1 year to correlate the MRI changes and neurodevelopmental outcome. Objectives: To find out different MRI findings in hypoxic ischemic encephalopathy babies. Assesment of severity of HIE from MR imaging and correlate these findings with clinical & neurodevelopmental outcome. Methods: All hemodynamically stable HIE babies irrespective of their severity were subjected to MRI between day 7 and day 21 of life and their findings were interpreted.

Objective: To evaluate clinico-demographic profile of hypertensive retinopathy cases in a tertiary care hospital of South Odisha, India. Materials and methods: This was a Cross-sectional study conducted in the department of Ophthalmology, SLN Medical College, Koraput (Odisha) from July 2021 to February 2022. A total of 226 hypertensive patients were examined out of which 100 were found to manifest hypertensive retinopathy changes. These 100 patients were further evaluated and analyzed. Sample size of the study was 100 number of hypertensive retinopathy patients. Different investigations done in the patients are Visual acuity, refraction, BP measurement, Tonometry, Fundus examination, Gonioscopy, B scan, Renal profile, Blood sugar estimation. Demographic parameters like sources of cases, age, gender, area wise distribution. The cases were again assessed to find out level of hypertension control, duration since hypertensive etc. Results: Hypertensive retinopathy grading distribution among hypertensives with controlled blood pressure was 56.25%,   31.25%  and  12.50% into Grade I, II and III respectively, showing lesser incidence of end organ damage with better control of blood pressure levels. Conclusion: There is a significant correlation between increasing age, blood pressure levels and severity of sclerotic changes with severity of retinopathy.

Introduction: In India, hydatid cysts of the liver are a serious yet untreated public health issue. Aim: To assess the sociodemographic traits, clinical manifestations, and treatment of individuals with liver hydatid cysts in a developing nation. Materials and methods: This retrospective study was conducted in Department of General Surgery, MKCG Medical College and Hospital, Berhampur over a period of 24 months from July 2019- June 2021. 23 individuals who were diagnosed with a liver hydatid cyst based on clinical symptoms, imaging tests, or serology underwent a retrospective, descriptive analysis. The data was evaluated and statistically analysed using IBM® SPSS® 23.0, for Windows®, to bring out the results of the study. Results: The patients' average age was 36, with the age range of 25 to 45 being the most frequently afflicted (10, 43.47%).The majority of the patients were female (56.5%). The most frequent symptoms were abdominal pain (21, 91.3%) and palpable liver (7, 30.4 %).The two main imaging tests utilised to make a diagnosis were computed tomography and abdominal ultrasonography. The most common type of cystic lesion was unilocular and anechoic.

Objective: The purpose was to study the ocular manifestations pattern and complications of vernal keratoconjunctivitis (VKC) and efficacy of corticosteroid, cyclosporine, alcaftadine. Material and methods: A Prospective study was done taking 227 patients from 15th Oct 2021 to 15th Mar 2022 in Department of Ophthalmology SLN Medical College and Hospital. Vernal Keratoconjunctivitis (VKC) was diagnosed basing on clinical presentation and scoring of signs and symptoms. Various investigations like slit-lamp biomicroscopy, keratometry, retinoscopy, distant direct, direct ophthalmoscopy and Corneal topography, fundus examination with +90D +20DVolk lenses done. Patients were allocated in 3 groups randomly for studying the efficacy of topical corticosteroid, cyclosporine and alcaftadine as monotherapy and first line therapy too. The results were analyzed after 4, 8 & 12 weeks. Visual acuity and ocular complications were recorded. Results: Most common age group involved was 5 year to 9 year and least were more than of 20 years. Among the patients, 171 (75.4%) were male and 56 (24.6%) were female between 1-30 years. Most common presentation was limbal form. Complications like shield ulcer found in 11 and keratoconus in 2 patients. There was significant reduction in sign and symptom score in topical corticosteroid and topical cyclosporine group.