Human amniotic fluid obtained near term was examined for total progesterone, progesterone binding and total protein. Samples from patients bearing male (M) fetuses had 25.5 ± 2.0 ng/ml (n = 45) and female (F) fetuses 23.8 ± 2.7 ng/ml (n = 32). Bound progesterone in undiluted fluid was 47.1 ± 2.2% (M) and 48.5 ± 2.1% (F) while total protein was 2.1 ± 0.2 mg/ml (M) and 2.3 ± 0.3 mg/ml (F). No sex differences could be found.
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