Objective: To evaluate the effect of propolis (a natural herb) against dentine hypersensitivity and to compare their effect with the controls.Methodology: Two databases were selected and searched for the relevant articles published up to 2019. Clinical trials involving propolis with other desensitizing agents and comparing it with controls were included involving patients that possess dentine hypersensitivity along with the extracted teeth. Nine clinical trials from 1999 to 2019 met the criteria involving 169 patients who had sensitivity and 214 extracted teeth were included in this scoping review.Results: Propolis was found to have a better desensitizing results than the controls, except Recaldent ™ which showed better results than Porpolis. Conclusion: Our results support the assertion that propolis is a good option which occludes the dentinal tubules and can relieve the symptoms of dentine hypersensitivity. However more clinical trials and high quality studies are needed to confirm its results in a better way.